Presentation
The organization of science into disciplines has led for a very long time to a fragmented vision of knowledge. Chemistry and biology, for example, were seen as neighboring fields rather than part of a shared continuum.The advent of biochemistry, structural biology, and more recently chemical biology or molecular medicine have helped to erase this boundary for a multi-scale understanding of living things, from molecules to ecosystems. The ICB project brings together teams from Université Paris Cité and the Institut Pasteur who share a common goal: strengthening the connection between chemistry and biology. Together, they are developing joint research projects, training opportunities, science outreach activities, and innovation initiatives that address key scientific and societal challenges.
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PhD position: Development of small RNA methylation site binders
This PhD proposal is part of a national collaborative project involving seven partners that focuses on the study and targeting of m6A methylations of Paramyxovirus RNAs. Epitranscriptomics modifications of viral RNA are key elements to regulate virus replication cycle...
PhD position: Direct Nucleic Acids Functionalization using α-silylated diazoalkynes (DNA-Fun)
Modified oligonucleotides have become indispensable tools in molecular diagnostics, gene regulation, therapeutics, and biotechnology. Selective functionalization at the 5′ and 3′ termini of DNA and RNA strands enables site-specific conjugation to a broad array of...
The Paramyxom6A Project, Laureate of the 2025 PEPR ANRS MIE Call for Projects
The Paramyxom6A project, led by Dr. Bruno Sargueil, is a laureate of the 2025 PEPR ANRS MIE call for projects. This project, involving 7 partners—including 3 teams from ICB—focuses on the study and targeting of m6A methylations of Paramyxovirus RNAs. For more...